Nobel prize in medicine awarded for cancer fighting immune research
US physician James Allison and Japanese scientist Tasuku Honjo win the 2018 Nobel Prize in medicine for discoveries that empower the immune system to attack cancer. Their work on turning off immune brakes led to drugs treating melanoma and other cancers, with Carter’s treatment cited as an example of impact.
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James Allison
University of Texas
Tasuku Honjo
Kyoto University
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Karolinska Institute
Allison
Honjo
Jedd Wolchok
Memorial Sloan Kettering Cancer Center
New York
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U.S
Jimmy Carter
Carter
Nadia Guerra
Imperial College London
University of California-Berkley
M.D. Anderson Cancer Center
Houston
Kyoto
Weather and historical temperature notes from Raleigh
Wind and sea forecasts for today and Wednesday show northeast winds at 4 to 8 knots with seas under 2 feet and cleared visibility, followed by south winds 8 to 16 knots and seas rising to 4 to 7 feet with visibility under 2 miles in a thunderstorm. A historical note recalls Raleigh recording its earliest freezing temperature on October 2, 1947, at 32 degrees, with later highs in the mid 80s and shifting pressure readings.
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Should we invite groomsman’s abusive partner to wedding
Bewildered bride seeks guidance on inviting the abusive former partner of a groomsman. The couple fears tension and damaged friendships, yet worry about harming relations if they exclude her. The columnist notes the partner’s history of emotional and physical abuse and social isolation.
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Mark
Bride
Ask Amy on coping with enmeshed relationships and drama
The column advises avoiding engagement with toxic behavior while preserving support for friends in need. It presents strategies for handling a manipulative partner, preserving friendships, and suggests demoting a groom’s ally to an honored guest to reduce conflict. It includes readers’ letters about Myrtle and teaching frustrations.
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Mark
Amy
Myrtle
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