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Antidepressants Ineffective for Bipolar Disorder in Major Study
A large federal NEJM study within STEP BD finds antidepressants do not relieve depressive symptoms when added to mood stabilizers for bipolar disorder, challenging current practice. Experts urge a mood stabilizer first, with limited alternatives for treatment.
MENTIONED IN THIS ARTICLE
New England Journal of Medicine
Thomas R. Insel
National Institute of Mental Health
Lori Altshuler
University of California
Los Angeles
Altshuler
Food and Drug Administration
NIMH