This is just the beginning! Our collection holds over 300 years of history, including rare newspapers, obituaries, marriage records, birth records, and so much more—most of which you won’t find anywhere else!
Study links CF to blocked CFTR protein on cell surface
New York AP reports a Genzyme study suggesting most cystic fibrosis cases arise when misformed CFTR protein never reaches the cell surface. Researchers injected mutant CFTR genes in monkey cells, finding about 70 percent produce an incompletely processed CFTR blocked by a cellular quality check. The finding supports exploring protein replacement or delivery of normal CFTR to lung cells as treatment possibilities.
MENTIONED IN THIS ARTICLE
New York
Alan Smith
United States
Cell
Smith
Genzyme Corp
bTadilogues
Mass
Michael Welsh
University of Iowa College of Medicine
Iowa City
Howard Hughes Medical Institute
Firet Stan, Smith
Genzyme
Robert Beall
The
Cystic Fibrosis Foundation