Gene that sets daily rhythm found in lab mice
Researchers led by Joseph Takahashi at Northwestern University located a key clock gene on mouse chromosome 5 that drives circadian cycles. The finding, to be reported in Science, could guide human clock gene research and pave the way for treatments for jet lag narcolepsy and sleep disorders.
MENTIONED IN THIS ARTICLE
Washington
Joseph Takahashi
Northwestern University
Science
Mr. Takahashi
Takahashi
Jean-Paul Spire
University of Chicago
Spire
The
American Association For the Advancement of Science
Frog skin extract bears morphine potential as painkiller
Los Angeles AP reports that a frog skin compound epibatidine shows stronger pain blocking in mice than morphine with fewer side effects. NIH researchers Barbara Badio and John Daly caution that human effectiveness remains unproven, as the Epipedobates tricolor extract behaves differently from opioid narcotics like morphine.
MENTIONED IN THIS ARTICLE
Los Angeles
Barbara Badio
John Daly
National Institutes of Health
Bethesda
Estrogen lowers thyroid-related bone thinning in older women
A Johns Hopkins UCSD study of 991 women aged 50 to 98 finds that those on thyroid hormone therapy who also take estrogen have bone health similar to nonusers. Higher levothyroxine doses linked to thinner bones. many elderly women reportedly received doses above recommended levels.
MENTIONED IN THIS ARTICLE
Chicago
David 8. Cooper
Sinai Hospital of
Baltimore
Mice produce human version of antibodies advance reported
Scientists at GenPharm International and collaborators report mice engineered with human genes can produce human like antibodies. This step may aid antibody based therapies for cancer and other diseases. Experts caution it remains unclear if this method yields better or safer antibodies than current techniques.
MENTIONED IN THIS ARTICLE
New York
GenPharm International
Mountain View
Calif
Nature
Sherie Morrison
University of California
Los Angeles
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