NIH suspends Alzheimer's prevention trial over naproxen risks
The NIH halted a 2500 participant study comparing naproxen and Celebrex for Alzheimer’s prevention after data showed naproxen raised cardiovascular events by about 50 percent versus placebo. Celebrex did not show immediate heart risk, though high doses were linked to heart attacks in another study. FDA officials urged caution and dosage adherence while studies continue.
MENTIONED IN THIS ARTICLE
Crawford
NBC
Sandra Kweder
FDA
NIH
Trial halted over heart risks in naproxen study
Federal regulators suspended the naproxen arm of a drug trial testing whether naproxen or Celebrex could lower Alzheimer's risk in healthy elderly at risk. Three years in, naproxen patients showed a 50 percent higher incidence of heart attack or stroke than placebo, prompting cautious review.
MENTIONED IN THIS ARTICLE
Washington
National Institutes of Health
Lester Crawford
Food and Drug Administration
The
Associated Press
Evening movie lineup at local theater
A slate of films listed with showtimes including A Series of Unfortunate Events Spanglish National Treasure Ocean's 12 The Incredibles Flight of Phoenix Christmas With the Kranks SpongeBob SquarePants and Blades Trinity. Major times span matinees and late shows with prices in the 275 990 range.
MENTIONED IN THIS ARTICLE
SpongeBob SquarePants
the Incredibles
Trinity
Mosul base attack kills 22 soldiers
An attack on a joint U S and Iraqi base near Mosul used rockets and mortars, killing 22 people and wounding 50. It targeted a dining hall, with casualties not confirmed as U S or Iraqi. The surge of violence follows Bush remarks on Iraqi forces potentially taking over later.
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Mosul
Washington
U.S
Iraq
Pentagon
United States
Bush
Fallujah
Baghdad
Holiday thanks for loyal patrons message
A warm seasonal note thanks readers for their patronage and wishes a merry Christmas, acknowledging support and goodwill during the holidays.
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Stayman
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