Drug research at Karolinska probes drug metabolism effects
At Karolinska Institute in Stockholm AP reports there is wide individual variability in drug response from zero to forty times, plus rapid metabolism after dosing. Dr. Bo Holmstedt leads studies into the clinical and toxicological implications of drug metabolism, including potential active metabolites and unforeseen side effects of chlorpromazine.
MENTIONED IN THIS ARTICLE
Alton Blakeslee
Associated Press
Stockholm
Sweden
Karolinska Institute
Bo Holmstedt
Quest to Assure Safer Drugs Through Ancient Plant Clues
Dr Holmstedt notes South American plants used by Indians may yield psychoactive compounds similar to serotonin. A specimen in the Kew Museum traced from Amazon, analyzed by Richard Spruce, hints primitive drugs inform brain function. Advances in chromatography and mass spectrometry enable detection of tiny drug traces and metabolites in blood, guiding safer therapies.
MENTIONED IN THIS ARTICLE
World Health Organization
U.S. Food and Drug Administration
Holmstedt
Dr. Holmstedt
Amazon River
Folke Stoquist
Charlotte Native Named Dean Elect at Tennessee Law School
Kenneth L. Penegar a 29 year old Charlotte native will become dean of the University of Tennessee College of Law as Dean Harold Warmer retires later this year. He earned both bachelor and law degrees from UNC Chapel Hill and studied law at Yale and attended the London School of Economics.
MENTIONED IN THIS ARTICLE
Knoxville
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