Rest gene regulator may explain protection from Alzheimer's
Harvard professor Bruce Yankner discussed REST, a brain gene regulator that suppresses cell death and reduces amyloid toxicity. Higher REST levels linked to preserved cognition in late life, suggesting a potential biomarker and new angle beyond amyloid and tau. REST activity could help explain cognitive reserve and inform lifestyle and intervention strategies.
MENTIONED IN THIS ARTICLE
Philadelphia
Bruce Yankner
Harvard University
University of Pennsylvania
REST
United States
Yankner
Joseph A. Pignolo
Penn
Smilow Center
Exercise fueling after workouts and the bar blend
A Minnesota cyclist Brendan Kennealy says extra beer calories justify workouts while Matthew Wildenauer describes a Cheers like gym vibe at Alchemy. PedalPubs mix social and physical activity, offering a keg on a bicycle trolley system. Yoga instructor Ted Roseen notes balanced enjoyment can aid progress. Roseen recalls offering treats after classes triggering taste satisfaction.
MENTIONED IN THIS ARTICLE
Brendan Kennealy
Bloomington
Minn
Matthew Wildenauer
Alchemy
Exercise boosts brain chemicals linked to mood
UC Davis Health System researchers found vigorous eight to twenty minute workouts raise glutamate and GABA in the anterior cingulate cortex and visual cortex, suggesting exercise replenishes mood-related neurochemicals. The study with 38 volunteers used MRI and a stationary bike to show heightened neurotransmitters only in exercising participants, with implications for treating major depressive disorder.
MENTIONED IN THIS ARTICLE
University of California, Davis
Journal of Neuroscience
UC Davis
Richard Maddock
Department of Psychiatry and Behavioral Sciences
Maddock
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