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Lidocaine's Unexpected Cardiac Rise From Dental Anesthetic to Heart Aid
The Swedish drug lidocaine, known as Xylocaine, shifted from dental and minor surgery use to emergency heart care. Astra's expansion, FDA approval in 1969, and its role in preventing fatal rhythms after heart attacks illustrate the drug's dramatic, cross‑domain impact and the broader search for new uses of old medicines.
MENTIONED IN THIS ARTICLE
Stockholm
Astra
Karolinska Hospital
Sodertalje
Jeading International Drug Corporation
Worcester
Mass
Scandinavia
France
Finland
Norway
England
West Ger
Belgium
Netherlands
Canada
Mexico
Colombia
Brazil
Argentina
Australia
Sigmund Freud
Karl Koller
Acta Medica Scandinavica
Gunnar Biorck
Gustav Adolf VI
Jan G. Waldenstrom
Anders Rosen
Serafimer Hospital
Swedish Food and Drug Administration
Henrik Lagerlof
University of Stockholm
Nils Lofgren
Lofgren
Bengt Lundquist
Lundquist
United States
Food and Drug Administration
Drug Agency
Dwight D. Eisenhower
Lyndon B. Johnson
Charlottesville
Medical Journal