Mutation Ties Thalassemia to Mental Retardation in Med World
Doctors at Oxford University report a genetic mutation found in three male thalassemia patients of Mediterranean descent. They suggest this 16th chromosome damage may explain why the victims were retarded, noting the finding as a potential link between the blood disease and cognitive impairment.
MENTIONED IN THIS ARTICLE
Daniel Q. Haney
Associated Press
Boston
Oxford University
England
Rare thalassemia case hints at chromosome 16 defect
Researchers linking a genetic variation to three northern European children with hemoglobin H disease suggest a chromosomal change on chromosome 16 may affect alpha globin genes and possibly cause nonspecific mental retardation. Mothers carried the trait but fathers were normal, implying a paternal or early embryonic mutation.
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Robert D. Koler
University of Oregon Medical School
Oxford
D.J. Weatherall
New England Journal of Medicine
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Koler
Odessa
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Cail Ws
Abo
E. Hwy
Chiropractic
Weriggerers