Cox II NSAIDS shake market over heart risk labels
An FDA panel advised updating labels for COX-2 inhibitors and NSAIDs after Merck, Pfizer, and others faced concerns about heart attack and stroke risks with Vioxx and Bextra. The panel urged warnings on Celebrex and related drugs, reflecting ongoing scrutiny of COX-2 inhibitors and NSAID cardiovascular safety.
MENTIONED IN THIS ARTICLE
Merck
FDA
Pfizer
Bextra
Alsoa
Painkiller Bextra recalled amid FDA warnings
Doctors brace for a flood of confused patients as the FDA orders stronger cardiovascular warnings on Bextra and 19 other NSAID prescription drugs. Pfizer pulls Bextra from the market at the agency's request amid concerns over heart attack and stroke risks with long term or high dose use.
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Washington
U.S
Pfizer Inc
Food and Drug Administration
FDA
Cox-2 drugs dominate US prescription totals despite market withdrawals
Pain relievers Bextra Vioxx and Celebrex accounted for over 50 million U S prescriptions last year before Bextra was pulled in 2004 and Vioxx earlier. FDA warns NSAIDs require caution with short term low dose use while studying cardiovascular risks across the class.
MENTIONED IN THIS ARTICLE
United States
U.S
Pfizer
Ex-guard testifies to Jackson mistreating boy at Neverland
Ralph Chacon, former Neverland security guard, testifies he saw Michael Jackson kiss, fondle, and perform oral sex on a boy who later received a settlement. A former maid testifies to inappropriate touching of Macaulay Culkin and three other boys as prosecutors frame a pattern of abuse.
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Jackson
Boy
Santa Maria
Calif
Michael Jackson
Neverland Ranch
Macaulay Culkin
Ralph Chacon
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