Genetic errors in cell division tied to aging study
Researchers at Scripps report 61 of 6 000 genes change markedly from age nine to ninety, implicating checkpoint genes that govern cell quality control in aging. The team suggests mismanaged checkpoints cause cascading genetic errors, potentially driving aging symptoms and decline. Further human studies are needed to confirm lab findings.
MENTIONED IN THIS ARTICLE
Washington
Science
Scripps Research Institute
la Jolla
Calif
Richard A. Lerner
Lerner
Leonard Guarente
Massachusetts Institute of Technology
Scripps
Aging alters gene expression and cell quality with age
Lerner cites a pattern of growing impairment across young to old and progeria cells. The study links aging to chromosomal transfer errors and weak quality controls, producing some missing chromosomes and up regulated genes. These changes may explain brittle bones and other aging traits.
MENTIONED IN THIS ARTICLE
Lerner
Curtis E Wheeler Wampum resident dies at 64
Curtis E Wheeler 64 of Wampum died March 30 2000 in Ellwood City Hospital. Born September 4 1935 in Grove City he was a BNZ Materials employee for 37 years and an Army veteran. He married Cheryl Holloway in 1987 and is survived by four daughters, three sons, two sisters and two brothers, with 12 grandchildren. Calling hours 11 am to 2 pm tomorrow at Marshall Funeral Home Wampum with a 2 pm service officiated by Cliff Reynolds. Burial in Clinton Cemetery.
MENTIONED IN THIS ARTICLE
Wampum
Curtis E. Wheeler
Ellwood City Hospital
Grove City
Curtis
Ruth Eagles Wheeler
Cheryl Holloway
Wheeler
BNZ Materials
Zelienople
Marshall Funeral Home
Main St
Funeral
Cliff Reynolds
Word Alive Church
Ellwood City
Clinton Cemetery
Robert J Beach Shenango China retiree obituary
Robert J Beach 76 of 809 Locust Street died March 29 2000 at Sharon Regional Hospital Born March 14 1924 in Harrisonburg Va he was the son of the late Russell and Katherine Phillips Beach He married Virginia Vitelli on April 19 1944 She survives Beach worked 40 years at the pottery and was a union officer A World War II Navy flight engineer He belonged to the Eagles and the AARP He was Roman Catholic He leaves daughter Roberta Beach New Castle two sons Robert R Beach Sharon and Larry Beach New Castle one brother Joseph Beach West Virginia two sisters Peg McCune and Bonnie Gill New Castle and four grandchildren He was predeceased by sister Margaret Wamner and granddaughter Whitney Beach There were no calling hours A blessing service was held this morning at Parkside Cemetery Officiating was Rev John Petrarulo of St Vitus Church Interment was in Parkside Cemetery Mausoleum Arrangements by Ed and Don DeCarbo Funeral Home 941 S Mill St
MENTIONED IN THIS ARTICLE
Shenango China
Robert J. Beach
Locust St
Sharon Regional Hospital
Harrisonburg
Russell
Katherine Phillips Beach
Virginia Vitelli
Beach
The
Pottery
Eagles
American Association of Retired Persons
Roberta Beach
New Castle
Robert R. Beach
Sharon
Larry Beach
Joseph Beach
West Vir
Ginia
Peg McCune
Bonnie Gill
Margaret Wamner
Whitney Beach
Parkside Cemetery
John Petrarulo
St. Vitus Church
Don DeCarbo
S. Mill St
Memorial service for Gladys Kray set at Harmony Baptist
A memorial service for Gladys Elno ra Kray, 96, formerly of New Castle, Largo Florida, will be held Tuesday at 2 p.m. in Harmony Baptist Church with Rev. F Dickson Marshall officiating. Burial will follow in Harmony Baptist Cemetery. Mrs Kray died January 3 2000.
MENTIONED IN THIS ARTICLE
New Castle
Gladys Elnora Kray
Harmony Baptist Church
F. Dickson Marshall
Harmony Baptist Cemetery
Kray
Largo
Fla
Furbys Pulled From Shelves Over Naughty Language
At a Reading Wal Mart in Exeter three dozen Furby Talking Buddies were returned after customers complained the dolls uttered a phrase that sounded like hug me though not clearly enunciated. Tiger Electronics said the toys cannot curse and customers simply misheard the sounds.
MENTIONED IN THIS ARTICLE
Reading
Wal- Mart
Exeter
Frank LaCoy
Tiger Electronics
Hasbro
Lawrence County Students Earn YSU Winter Degrees
Lawrence County students received degrees from Youngstown State University at winter commencement. New Wilmington graduate Joseph Misiaszek earned an MBA. Pulaski graduates include Steven Miller with a bachelor of engineering and Rebecca Abramson and Wendy Hepler with business administration and nursing degrees respectively. Enon Valley’s Patricia Miller earned an MS in education. New Castle graduates are Michael Hooven with a BS in education, Samuel Abraham III with an AS with honors, Richard Russo with an AS with high honors, Paul Alam with a BS in business administration magna cum laude, and David Fair with an MS in engineering. Edinburg’s Toni Tricolo earned an MS in education, Lisa Nero and John Minteer earned BS degrees in applied science. Ellwood City’s Tammi Schmalenberger earned a BS in applied science.
MENTIONED IN THIS ARTICLE
Lawrence County
Youngstown State University
New Wilmington
Joseph Michael Misiaszek
W. Neshannock Ave
Pulaski
Steven James Miller
Maple Circle
Rebecca Jane Abramson
Wendy Lynn Hepler
Enon Valley
Patricia Kay Miller
Seltzer Lane
New Castle
Michael Scott Hooven
S. Scotland Lane
Samuel J. Abraham III
Ellwood City
Tammi Lynn Schmalenberger
Silver Drive
Three Charged After South Side Parking Lot Incident
Three people faced charges after tangling with police in a West Long Avenue parking lot. Dennis McNeish, 39, Mary McNeish, 36, and Jon Kingensmith, 39, were arrested with counts including aggravated assault and obstructing police. Officers Pruchnik Conti and Viggiano were injured during the arrests.
MENTIONED IN THIS ARTICLE
South Side
West Long Avenue
Den
Nis McNeish
Beechwood Blvd
Pulaski
Mary McNeish
Jon Klingensmith
Dennis McNeish
Melissa Amodie
Klingensmith
Also Mentioned on This Page
Curtis Wheeler
Hermitage
Robert Beach
Gladys Kray
OF Lim
E. W. Swing
Saan
Protech Security Systems, Inc
Bell Atlantic
Boardman-Poland Rd
Southern Blvd
Wwwacnewsonline
Celle Lehss
N. Mercer St
James F. Rupp
Merit Plaza
K. Pulaski Club
Sunny Ave. Park
Atlantic Ave
Theirs
Women's Health Center
Ours
S. Erzurum
M.D
New Castile
PTV
Peetlace
Healthywomen.com
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