3TC and AZT combo shows promise as initial AIDS therapy
FDA advisers urged caution though endorsing 3TC as a first therapy with AZT. The combo boosted CD4 counts and lowered HIV blood levels by up to 92 percent, especially in patients never treated with AZT. Glaxo seeks approval for adults and potentially children with a strawberry banana flavored form, amid questions on timing and safety including pancreatitis risk.
MENTIONED IN THIS ARTICLE
Silver Spring
Food and Drug Administration
Glaxo Wellcome
FDA
Douglas Mayers
Walter Reed Army Institute of Research
Washington
Glaxo
Marc Rubin
Research Triangle Park
N.C
Rubin
Epivir
3TC
Lamivudine
Biochem Pharma
Laval
Quebec
Canada
Scott Hammer
New England Deaconess Hospital
Boston
Ust
David Barr
New York
Researcher links apo E4 gene to Alzheimer's cause
Duke neurology chair Dr. Allen Roses reports a new view that apo E4 weakens brain cell nutrient plumbing and waste removal, potentially delaying Alzheimer's by decades. He notes E4 raises risk after head injury and contrasts with other experts who see E4 as a risk factor, not the direct cause. About 4 million Americans have the disease, with 100,000 deaths annually.
MENTIONED IN THIS ARTICLE
Duruam
N.C
Allen Roses
Duke University Medical Center
Council For the Advancement of Science
Roses
Dennis Selkoe
Harvard Medical School
Selkoe
Four dead in Charlestown restaurant shooting
Two gunmen opened fire inside the 99 Restaurant in Charlestown, killing four customers and wounding a fifth. Police arrested Damien Clemente of Medford and Vincent John Perez of Boston, who face four counts of homicide and weapons charges. The motive remains undetermined and witnesses described chaotic scenes as patrons fled.
MENTIONED IN THIS ARTICLE
Boston
Charlestown
Paul Evans
Steve Maurer
Boston Harbor
Mystic River
Bunker Hill Monument
Terry Titcomb
GOP considers retroactive 500 per child tax credit
Leading Republicans discuss making the 500 per child tax credit retroactive to 1995 as part of a balanced budget package. Armey backs the idea while Gingrich and Dole show interest, with potential benefit to taxpayers when they file in 1996.
MENTIONED IN THIS ARTICLE
GOP
Washington
House
Dick Armey
Armey
R-Tex
Newt Gingrich
Senate
Bob Dole
Kan
Cost of retroactive child credit sparks Senate House clash
The cost of retroactive child tax credits tops 20 billion in the Senate bill, with earnings limits. House plan offers full credit up to 200000, while Senate extends full credit to single parents up to 75000 and couples to 110000. Republicans warn of unsustainable revenue losses in year one. Other options include asset sales and retroactive capital gains tax cuts timing differs between House and Senate bills.
MENTIONED IN THIS ARTICLE
Senate
Rep
William Archer
House
Ways and Means
Online panels and chats feature Moseley Braun and sports figures
Tribune Media Service lists evening online events across platforms AOL MSN CompuServe Prodigy and Spin Online. Notable talks include Sen Carol Moseley Braun on AOL discussing local elections with Ili nois legislator at ACLU Coliseum and tennis legends Jimmy Connors Bjorn Borg and Andre Gomez on MSN about the sport at their venue.
MENTIONED IN THIS ARTICLE
Carol Moseley-Braun
America Online
Ilinois
ACLU
Coliseum
Jimmy Connors
Bjorn Borg
Andre Gomez
Microsoft
MSN
Stefan Johansson
CompuServe
Motor Sports Forum
Blair Kamin
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Celebrity Circle
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Mark Kates
Geffen
America
Globe
Mike Rubinelli
Odeon
Kevin Smith
Malltrats
Clerks
Spin
Drew Carey
Prodigy
Lance Rose
NetLaw
Media Lawyer
Business Week
Journal-World Daily
Imvucalmve
Jworld.com
Kansas
Kansas Cash
38Th Street
South Lawrence
Access
Lawrence City
Dread Clinical Supplies Inc