Global trial tests hypertension drug for isolated systolic BP
A five year study led by Dr. John Kostis at UMDNJ begins in 16 countries to see if omapatrilat can prevent artery stiffening and reduce deaths or heart events in seniors with isolated systolic hypertension. About 12,600 patients at 900 sites will be enrolled.
MENTIONED IN THIS ARTICLE
Trenton
N.J
University of Medicine and Dentistry of
New Jersey
John B. Kostis
Department of Medicine
Umdnj-Robert Wood Johnson Medical School
New Brunswick
Kostis
Bristol-Myers Squibb Co
Omapatrilat trial eyed to treat isolated systolic hypertension
In a Bristol-Myers Squibb funded study led by Kostis, elderly patients with systolic hypertension will test omapatrilat versus placebo to see if lowering systolic pressure improves outcomes. The trial, to be monitored by FDA speeded review, targets 65 plus with 141 to 159 systolic and diastolic below 90, with half receiving 20 or 40 mg daily. Alfred Feld, a first recruit, hopes the drug slows heart risk and improves function.
MENTIONED IN THIS ARTICLE
Kostis
Bristol-Myers Squibb
Princeton
Federal Food and Drug Administration
Alfred Feld
Feld
Jeffrey Cutler
National Heart, Lung and Blood Institute
Cutler
Publishers Clearing House faces lawsuit over mailings
Deborah Holland of Publishers Clearing House defends the firm against claims of misleading mail. The Port Washington company, active since 1953, has run sweepstakes since 1967 and says it donates 40 percent of profits to charity. In recent years, settlements by similar firms include 33 million and 6.9 million payouts.
MENTIONED IN THIS ARTICLE
Moore
Deborah Holland
Publishers Clearing House
Holland
Port Washington, N.Y
Christopher Irving
American Family Enterprises
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Mississippi
American Red Cross
Red Cross
Harry McKneely & Son
Susan McKneely Fowler
Hammond
Tangipahoa Parish
Sheriff's Department
ARLE
Care Inc
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