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Scientists identify SATB1 breast cancer gene as metastasis trigger
Montreal linked study in Nature reports SATB1 as a master regulator that flips thousands of genes in tumor cells, driving metastasis. Experiments in mice show SATB1 suppression greatly reduces lung nodules, while overexpression accelerates growth. researchers aim for targeted nanocapsule inhibitors, with prognostic tools expected soon.
MENTIONED IN THIS ARTICLE
U.S
Nature
Termumi Kohci-Shigematsu
Lawrence Berkeley National Laboratory
Berkeley
Calif
AFP
Impo
Kohci-Shigematsu