Gene silencing advances target dominant neurological diseases
Iowa City researchers at the University of Iowa report progress in gene silencing of mutant genes linked to dominantly inherited neurological disorders. Using human tissue cultures, the team silenced a MacDonald Joseph disease gene and a Tau protein mutation associated with inherited dementia, describing a potential approach to neurodegenerative conditions.
MENTIONED IN THIS ARTICLE
Ine
Iowa City
University of Iowa
The
National Academy of Sciences
RNA interference targets single nucleotide polymorphisms in disease genes
The study shows RNA interference can distinguish genes by a single nucleotide polymorphism next to a mutated sequence linked to Machado Joseph and seven other neurodegenerative disorders. Researchers including Henry Paulson used human tissue cultures, first failing to silence the disease gene then succeeding by targeting the SNP. work on mice follows. NIH funded the investigation with team members Victor Miller Haibin Xia Ginger Marrs Cynthia Gouvion Gloria Lee Beverly Davidson.
MENTIONED IN THIS ARTICLE
Henry Paulson
Paulson
Victor Miller
Haibin Xia
Ginger Marrs
Cynthia Gouvion
Gloria Lee
Beverly Davidson
Davidson
Roy J. Carver
State Patrol and Iowa Wireless push cell phone guidelines
The Gazette reports the Iowa State Patrol partners with Iowa Wireless to promote voluntary cell phone use guidelines to reduce distracted driving. Lt. Robert Hansen cites about 6,000 Iowa crashes annually from distracted driving, though phone specific causes are uncertain. A 2001 accident report form requiring phone-use boxes is not yet fully analyzed.
MENTIONED IN THIS ARTICLE
the Gazette
Iowa
Iowa State Patrol
Iowa Wireless
Robert Hansen
Drivers' cell phone guidelines in use and outlook
Guidelines urge hands free devices and voice dialing to reduce driving distractions. Passengers should dial or answer calls. Traffic safety officials note rising distraction risks as maps and phone features spread in new cars. The State Patrol backs phone use for reporting hazards and accidents. A year old 911 routing system aims to trace drop out calls more easily. weather number dialing also noted.
MENTIONED IN THIS ARTICLE
State Patrol
Hansen
Educational canoe trip on Maquoketa River opens Sunday
A weeklong Maquoketa River canoe trip begins Sunday to focus on watersheds and Iowa water quality. Project AWARE, sponsored by the DNR Keepers of the Land and IOWATER, will host volunteers from Backbone State Park to the river’s confluence with the Mississippi. Geologists, botanists, water quality scientists, and wildlife professionals will join, with nightly programs on topics related to Iowa’s river ecosystem.
MENTIONED IN THIS ARTICLE
the Gazette
Maquoketa
Iowa
Project
Department of Natural Resources Keepers of the Land
Iowater Citizen
DNR
Jeff Vonk
Backbone State Park
Mississippi River
Maquoketa River
Volunteer Registration Offers Week Long Water Quality Session
To sign up for details call Tom ONeill at 515 281 4539 or visit AWARE online at www iowadar com volunteer aware html freshwater mussels and aquatic life to geology and water quality session leaders include Iowa poet Michael Carey former DNA Director Paul Johnson and Chad Pre gracke of the Mississippi River Clean Rivers project registered volunteers invited for an afternoon a day or the entire week free camping provided registration free and meals available for about 15 dollars per day
MENTIONED IN THIS ARTICLE
Tom O'Neill
AWARE
Iowadar.com
Iowa
Michael Carey
DNA
Paul Johnson
Chad Pregracke
Mississippi River Clean Rivers Project
Lowans favor tax cut over business fund
Iowa adults prefer cutting personal income taxes over creating an economic development fund to aid biotechnology and other industries. The Iowa Values Fund proposal drew 56 percent in support for grants and loans to expand targeted businesses, while 34 percent opposed and 10 percent unsure. The poll, taken May 17–20, also notes 22 percent favor tax reform as the best move for the economy, with 18 percent backing recreation and cultural improvements.
MENTIONED IN THIS ARTICLE
DES Moines
Tom Vilsack
Iowa
Vilsack
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National Institutes of Health
Iowa Department of Transportation
Dubuque
Brian Lex
National
Mississippi River Museum and Aquarium
Des Moines Register
Sea Room
Wicker & Gifts
Third Ave
Cedar Rapids
Foot & Ankle Clinic
Robert M. Caldwe Dpm
Facfas
Vane
Sime Lake Gail
Life Insurance Society
Eugene Edelen
FIC
Johnson Ave
America
Fraterni
Fe Insurance Society
Cence Bock Island
Illinoes
Lern-Woodmen.org
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