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Diabetes drug Avandia may raise osteoporosis risk
New findings suggest long term rosiglitazone use, the active ingredient in Avandia, increases bone resorption in mice, offering a possible mechanism for higher fracture risk among diabetics. Researchers warn caution for patients at fracture risk and note potential combined therapies and safer drug development.
MENTIONED IN THIS ARTICLE
Washington
Nature Medicine
Avandia
GlaxoSmithKline
Ronald M. Evans
Salk Institute For Biological Studies
la Jolla
Calif
United States
Evans
Howard Hughes Medical Institute
National Institutes of Health