Internet Payments

Secure & Reliable

Your data is encrypted and secure with us.
Godaddyseal image
VeraSafe Security Seal

Lethbridge Herald Newspaper Archives

- Page 12

Join us for 7 days to view your results

Enter your details to get started

or Login

What will you discover?

  • 108,666,265 Obituaries
  • 86,129,063 Archives
  • Birth & Marriages
  • Arrests & legal notices
  • And so much more
Issue Date:
Pages Available: 22

Search All United States newspapers

Research your ancestors and family tree, historical events, famous people and so much more!

Browse U.S. Newspaper Archives


Select the state you are looking for from the map or the list below

OCR Text

Lethbridge Herald, The (Newspaper) - October 25, 1971, Lethbridge, Alberta 12 THE LETHBRIDOE HERAID Monday, Otlober 35, 1971 Government, drug industry seek non-addicting substitute for methadone By KI1ANK CAREY WASHINGTON (AP) An almost unprecedented research quest bv government and lhe drug industry lo find a safer, non-addicting' and longer-lasting substitute for the controversial drug methadone may take shape in the war against heroin addiction. Two-pronged goal of tiie proposed venture is to: D eve op "heroin antagonists" that would thwart heroin addiction for anywhere from a week lo more than a month with a single dose, compared with once-a-day requirements for methadone. even develop a "vaccine" for more or less permanent protection against heroin addiction. Methadone is the narcotic drug already being given to about of the to United States heroin addicts to block their "heroin hunger." Like heroin, methadcne is highly addictive and illicit traffic. 11, too, can be a killer if improperly used. A new variety of methadone lias been developed rated as effective for up to 72 hours, compared with 24 hours for the present form. But it still is in relatively short supply and has the same potential dangers as conventional meUiadonc. The idea to join forces for a new anti-heroin weapon came from tiie drug industry, which proposed pooling research skills and facilities by 123 of the country's fiercely competitive phar-m a c e u t i c a 1 manufacturing firms. The government has bee.-i invited hut has made no commitment. Anti-trust laws would have to eased to get the heroin research started. FAVOR METHADONE Meanwhile, although strongly backing the proposed new research venture to find substitutes for methadone, President Nikon's new special action office for drug abuse by executive is pushing for expanded use of methadone. The head of the office, Dr. Jerome II. Jade, concedes that methadone is by no means the perfect answer. But Jaffe and his aides say they hope to have new treatment and rehabilitation facilities reach up to heroin addicts over the next three with msthadono playing a large role. Jaffe said in an interview that his office believes methadone-maintenance, used as an adjunct to psychiatric and other drag-free n-.sihocls, is better than anti-heroin programs employing drug -free methcds alone. Estimates are that it costs a heroin addict 000 yearly to finance his and that he must steal up to in jewels and other goods to get. that kind cf moiiey from a unless he steals it in cash, or, in tiie ease of a prostitute, earns it. It costs about yearly an addict on methadone. Mcthadcno is a synthetic cp-k'.e developed by German scientists during the Second World War. II was designed originally as a new pain-killer, but in the it was also found capable of blocking a heroin addict's craving for the drug, and his ability to get "high" on it. Dr. Vincent P. Dole of Rockefeller University, New York, and Dr. Marie Nyswander, his wife, pioneered the clinical use of the drug as a heroin-Mocker in 1SG4. They claim a high percentage of success in getting hard-core addicts to kick or reduce their habit, and return to jobs or school. LOTS OF CRITICS But, until recently at least the drug has had a stormy history, with some doctors arguing that its use merely means substituting one addictive narcotic for another. Other opponents have said that addicts chosen from the still-experimental program carefully screened, and so highly motivated, that it would be hard not lo succeed. They say psychological, drug-free treatment methods alone could succeed with sucli people. Despite criticism, investiga-tional use of methadone as a heroin Mocker has steadily expanded since in government-supported or private pro-giams. Today there are alwut I1CO projects throughout the U.S., serving an estimated heroin addicts. So far, methadone has been permitted only experimentally, but Dr. Elmer A. Gardner of the bureau of drugs in (he Food ar.d Drug Administration said in an interview the FDA may change this "relatively soon." He envisaged a system of "conditional marketing" of the initially at whereby licensed and registered institutions and individual doctors could procure it on the open market. Doctors still would be required to have special resources and facilities to or prescribe the drag and to keep records of its use. So far. he said, fair melha-done-mainlenance projects have been ordered closed and at two more will be closed for violating rules on clinical experiments with the drug. In most of (lie closures, Gardner said, FDA inspectors had found evidence of mcthadone being "sold in the streets" by mp.thadone-treated addicts. He said Uiat metbadone-ad-minislered orally in an orange drink to approved projects-does not produce a euphoric "high." But a "high" can result if it is injected. Some addicts have learned how to convert it into injectable form by such methods as distillation, he said. NO-HIGH SUBSTITUTES lift is produced, however, by narcotic antagonists, which the drug industry wants to develop. The antagonists are drugs designed to prevent heroin and other narcotics from reaching the nervous system. the antagonists dca't wipe out an addict's physical craving for heroin, for example, they prevent him from getting a "high" H he does inject or sniff heroin. Thus, there's no point in taking heroin. Also, unlike mclhadone, the antagonists are non-narcotic and non-addicting. The three most promising antagonists developed thus far are still hi UK investigation stage, and all of them have certain drawbacks. They are: Naloxone: This is a highly-effective narcotic Mocker, but it must be given every four to five hours. It is derived from a substance present in opium, so it's expensive and hard for researchers to import. Cyclazocine; This is a synthetic, man-made drug, and can be produced in unlimited quantities. A single dose is effective for about 24 hours. But it can produce undesirable, even dangerous, side effects, including LSD-like hallucinations, under certain This Is Ihe newest one, made by a chemical "marriage" of certain components of naloxone and cycla-zccinc. In tests on healthy, non-addict human volunteers it proved to have far fewer and less severe side-effects than cy-ciazocine. But its heroin-blocking effect is not as long. Compared with naioxoiie, however, it is twice as long-lasting and is eifeclive at deses from one-tenth to one-twentieth as large and therefore cheaper. Meanwhile research to find better antagonists goes on. friend BOSTON (AP) Boston Patrolman Cecil E. Fox, 39, has been relieved of duty pending the outcome of the police investigation of the fatal shooting Thursday of fellow Patrolman Samuel J. Reynolds, 33. Police quoted Cox as saying he accidentally shot Reynolds, a friend, while attempting to fire a warning shot after a car. CENTRE VILLAGE DAY TUESDAY, OCT. 26 PERSONAL SHOPPING ONLY PLEASE MACLEODS SUDDEN BEAUTY HAIR SPRAY Reg. 84c SPECIAL 31.49 LIMIT OF THREE PER CUSTOMER 36" CORDUROY Regular 1.98 yard SPECIAL, YARD 1.49 TROUBLE LAMP Regular 3.59 SPECIAL 1.49 UMIT ONE PER CUSTOMER 149 Men's Nylon Socks- Bottlc 3-Ply Nylon Wool Asst Door Mats 1 Shel1 Oil 49 O'Henry 1 Boys' Boxer Pants D..b......_ Car Seat Cushion 1 49 Girls' T Shirts Boys' T-Shirts long sleeved. Reg. 1.69..... long Perma-preu. Reg. 1.89 1" Ladies' Glove and Scarf Set 1" Imperial .22 Shells long and long Rifle 1 Continental Bed Legs 149 Speed Driver Set... 1 ;