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Lethbridge Herald Newspaper Archives

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Lethbridge Herald, The (Newspaper) - May 10, 1972, Lethbridge, Alberta More research planned on use Herald Ottawa Bureau OTTAWA How early in life a person first starts using ean- nabis might be more important in terms of some long-term ef- fects than the length of time the individual uses cannabis, just- completed experiments with rats and active ingre- dient of sug- gest. If the users are young enough when they start, they might develop smaller organs- including smaller similar users who start later in life, the rat experiments at Car- leton University suggest. A significant difference in rat brain size between young and adult rats given THC was the most "unexpected1' difference uncovered by Psychologist.? Dr. Peter Fried and Carol Barnes at the conclusion of a four- month-long, federally-funded search by Miss Barnes study of some 120 rats. summer. Tlie younger rat users of THC j This time, she will use "mini also developed a tendency to "carrv-over" some effects of .'inl do her research at this latest one, the rats are given a erance would develop. This par- dose of 4 milligrams of THC per ticular group had been given kilogram of body weight. In a THC during all three 40-day pe- human, this is estimated to riods. the drug during periods of absti- nence, so that thev developed "tolerance" to renewed or in- creased doses of THC faslcr than companion rats who were firrt cxnoscd to TI1C ns adults. Finally, the youthful users ex- hibited a greater tendency to repair what the experimenters viewed as physical damage to certain body organs as a result of long-term use than either older chronic users or both younft and old short-term users of THC. The reasons for and the sig- nificance if these differences are not fully understood. Yet the findings are important enough that the federal govern- ment will fund continued re- the Ottawa research laborator- ies of tiie federal health protec- tion branch, formerly the food and drug directorate. The studies on the special breed of "mini-pigs" should bet- ter determine how applicable the findings of the rat studies arc to man, in terms of the effects of THC on social behav- ior as well as in terms of possi- ble physical effects on tissues. The latest Carleton study is one of a series of animal experi- ments directed by Dr. Fried, lo determine the effects of short and long-term doses of moder- ately high amounts of THC on rats with an eye on implica- tions for human use of canna- bis. In most studies, including this STRETCHING A POINTER commuters In Tokyo's Shinjuku station can't help but notice a life-sized stuffed giraffe advertising a neighboring zoo. The giraffe is mechanically nibbling and swinging its long neck and was designed to calch the eye of the passerby. equal the effect of smoking eight average marijuana retles. When (he double dose of THC ciga-1 was given, the adult rats in this chronic group exhibited a slight To date, Dr. Fried's studies but noticeable impairment. The young rats showed no impair- have revealed that "first-time users" of THC exhibit Hie high- 1 ment. est impairment, as measured by simple rat motor co-ordination tests. The long-term users tend to develop a "tolerance" to the drug. In similar tests, they match the rats in the "control" no drug is given performance. The long-term or chronic users seem to learn to "cope" with the drug in some way. In tills latest study, the inten- tion was determine if there is any difference resulting from tile age of "first exposure" to THC. There were two control groups and four THC groups. Each group consisted of "in- fant" rats and "adult" rats. The study was split into three con- secutive periods of 40 days, with the testing during the final pe- riod. The "infant" rats started off at 30 days of age. The "adult" rats were 90 days old at the start. A rat is considered to reach maturity at about 60 days of age. OF5 czcsewyd age. Miss Barnes gave one of the experimental groups THC dur- ing the first 40-day period, no THC during the second, and THC again during the final test- ing period. She noticed a difference be- tween young and old rats. The young starters required only eight doses of THC before they developed tolerance to the drug. The adult rats required almost twice as many doses. Miss Barnes theorizes that the young rats have "carried-over" some effect of the drug during the 40-day abstinence from their first 40-day drug period. She delected the same phe- nomenon in another group when the rats were given a double dose, to see whetlier a new lol- After the experiments were completed, a crude analysis was done of the weights of selected organs from the rats. Generally, there was a notice- able change in weight of most organs of rats in the THC groups compared with rats in the control groups. The changes were greater in the short-term users than the long-term user groups, suggesting the damage caused by THC was being re- paired by the chronic groups at the same time as they were de- veloping "tolerance" to the THC. But in the two "carry-over" groups mentioned above, the in- f a n t rats had significantly smaller sized brains in terms of icientisls stress the organ analysis part of the experiment i was not as carefully controlled as the co-ordination tests. They would now like to deter- mine what portions of the brain might be affected by the reduc- tion in size, and why it occurs. In more general terms, they are concerned that giving the THC to the young rats may in some way affect their develop- ment and result in effects later in life that do not occur in rate first exposed to the drug as adults. No one else gives you this much Property law eased in Mexico A couple of years back, II you wanted lo fulfil that dream of owning a little place by the sea in Acapulco, you had to ac- quire it through a series of le- gal subterfuges that cost almost as much as the property itself. This was because the Mexi- can Constitution stated that "No foreigner can directly own real estate within 100 kilometers from the borders and 50 ters from the coasts." Since Acapulco is the only seaside re- sort in the world that can guar- antee 360 days of perfect weath- er and sunshine every year, thousands of Americans and Ca- nadians persisted through the massive legal red tape to ac- quire their own little piece of "Paradise." But now (since mid 1971) President Echeverria has made it simple and legal for you to buy a lot, a villa or a condom- inium apartment and you will receive title almost as if you were a Mexican citizen. His purpose in liberalizing the law is to attract more foreign capi- tal to accelerate the industrial and tourist development of Mex- ico and already the results are beginning to show. So if Acapulco Is your dream Shangri-la, fly down and take a look at what is avail- able before the rush caused by the new law inflates property prices beyond the reach of your budget. A translation of the new law may be had free by writing almost any bank or real estate company in Acapulco. Wednesday May 10, 1972 THE tETHBRIDG! HERAID 39 Floalcl holidays on the Shannon KILLALOE, Co. River Floatels, operating frrun its new base at Killaloo, v.ill run 15-day full river and eight-day inland Shannon cruises in 1972. ILs foirr floatels, each cam-- ing 12 passengers, will operate 15-day cruises from about and eight-days from (transfers The full river series features 250 miles of cruising with calls at his- toric landmarks. The vessels berth from April to September each evening. villages and towns Careers in Management SCOPE FOR INDIVIDUAL GROWTH AND ADVANCEMENT OPPORTUNITIES FOR FURTHER EDUCATION SALARY FUILY COMMENSURATE WITH QUALIFICATIONS AND EXPERIENCE ATTRACTIVE FRINGE BENEFIT PROGRAMS We have a number of openings lead- ing lo management positioni for In- dividuals with financial or olher business experience. Successful can- didates will receive comprehensive training supplemented by formal instruction courses followed by interesting assignments In a vari- ety of branches throughout Alberto. Subsc-quc-nl openings will occur in a wide variety of situations which we would be pleased 10 discuss with in- terested applicants. Promotion is based on merit and opportunities for DESIRED OUAtlFICATIONS Those we ore seeking should posseEl -t least a year or two business ex- perience preferably in a financial setting. Previous training will be core-fully evaluated but in the final analysis maturity, initiative and a strong interest in working successfully with others will be the most impor- tant criteria in selecting candidatei. For further information telephoni cr B. K. Wershler Employment Officer P.O. Bag Service 2534 Calgary 2, Alberfa Telephone: 268-3484 or call on any of our branch managers 1. 73 horsepower engine 2. Four-speed transmission 3. Front disc brak 4. Fully reclining bucket seats 5. Electric rear window defroster 6. Whitewall tires 7. Full vinyl interior 8. Electric windshield washer 9. Two-speed windshield wipers 10. Padded recessed dash 11. Collapsible steering column 12. Glove box 13. Cigarette lighter 14. Heavy duty heater- defroster 15. Three-position courtesy lights 16. Hand brake warning light 17. Three point retractable seat belts IS. Power boosted fresh- flow ventilation 19. Swing-out side rear windows 20. Unit body construction 21. 60 amp. hr. battery Dual braking system Wrap around bumpers Side running lights Back-up lights Washable and removable trunk mat Recessed spare tire Tool kit and jack Electrophorus paint application 30. Four-way flashers TOYOTA 27. 28. 29. for this much retail price Corolla 1200 2-door sedan KO.P5. Vancouver, Calgary, and Moncton; local frripht. lice-life, and taxes extra. Hni Toyota cars arc sold and serviced from coast to coast in Canada and throughout the world. LETHBRIDGE Toyota Travel Centre Box 1202 Coutts Highway Tel. 327-3165, 327-3711 CARDSTON Wolff Son Toyota Tol. 453-3252 MILK RIVER I TABER Madge Equipment Ltd.I Kenway Toyota Box 299 Tel. 647-3838, 447-39391 Box 1008 Tel. 223-3434 SPEC GIFT IDEAS FOR MOM Choosing For quality and price? Then buy our own Kenmore brand. ..always a great buy at regular price, now you get extra savings while they're on sale. Backed by our 1-year guarantee. A great choice! 2-Speed Electric Blender 1 C 00 fclectric Can Opener 9.98 Electric Knifs 1 7.98 Is price n bis factor in ynnr choice? Then choose from our selection everyday low They're among the brsl vnlins in town...ami that mate living wiihin your budget a lot easier! Kenmore 10 Speed Blender Avocado, Whito or Gold. Aft Reg. ..........HI ,77 Kenmore Avocado. Whila or Gold. 1 Q Reg. 17.77 Kenmore Electric Knife With Reg. 26.99 Quality Costs No More At Simpsons-Scars STORE HOURS: Open Dolly 9 a.m. lo p.m. Thursday and Friday 9 a.m. to 9 p.m. Contro Village. Telephone 328-9231 ;