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Lethbridge Herald Newspaper Archives

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Lethbridge Herald, The (Newspaper) - February 15, 1972, Lethbridge, Alberta JO THE ir.THBRIPCE HERALD Tuoidoy, February 11. 1771 Doclui's Ircahncnl sclerosis patients 'j take I part' in tests Tiicr.! lli.'ii Muni' ;lu'. imiy it; DSCfll! n hT.'lHlliMll for this chronic (.Tipping dist'aj-c. Vr, Ali'.v .M r rh t1 r.s on singed il is not a cure for ihc- rliM'a.so. nr even ;t major biviLklhrouyh in rc- scnrch. Bui he down't deny lhal lie TKLLs STOHV Anne Da.vlrr. lJ-r ilii in vlnic'lor. IVIK of nuTling :ui- ilmr Clirfm-il In in llir Virgin Islands ni-ccinbcr. vlir him snibn flirinsj instructions Mir -tins snhprmacd In a l'..s. I-'nilrral (.rand .liivy to Irll her stnry in ilip Ilnuiinl Ilimlics aiiln- rasp. and his n.'-MJciatc. Dr. IVlc-r Sekmd, hiivp found nupi'me- im-nl in sonic of the patients under his care. "It's jnsl Unit ii's too o.irly lit be alile to loll if we're on (lie right track." Dr. MePIier.son, ziclmp he.-id of the department of immu- nology at [he University of Al- borU'i, Morks bolh in l-hc aroa of basic immunology, com- pletely in the laboratory, and in clinical research, with pa- lionLs on Hie wards. ATTEMPT AT BRIDGE "All of us working in immu- nology at the University of Al- berta are attempting lo form a bridge between basic exper- imental rest-arch and Uie clin- fpplicnlion of be said in an interview. .VfPJicrson and Selaml are experimenting with a basie prulnn molecule thai is Hul cited from brain tissue from cadavers. Either the whole molecule or a specific group of nine amino acids from it will cause a clinical disease with a reac- tion in the brain and spinal of guinea pigs which closely resembles that seen in humans wilh multiple scle- rosis MS, as il is .isnaily called, is a disease that affrds the nervous syslcm causing little, thick plaques or patches lo fnnn. These p I a q u n s are starred nerve tissue and re- sult in the nciiiological com- plainls. such as Ins? of sensa- IJon. unaknc.v5 ,7m) lack of cit-ordiualion in nniLS and H'S-s. CAISI-: is II is not known v.lial causes MS, lint Dr. McPherson said il appears the patches may he the of an Jmimuic reac- tion m (he affected reaction of (lie nen't1 tissue to some [orcign substance that has entered (he body at some Lime. The immune reaction that the doctors ean cause in guinea pips by injecting the proleiu molecule or (.lie nine specific amino acids is simi- lar. II is called experimental allergic encephalomvelitis, or EALC. Tliis preliiiiijiary fact-find- ing work in the experimental disease has gone on in many centres like the University of .Alberta. Dr. .McPherson said. Eci-h gniiip now is trying to find additional information thai might provide another clue to the mystery of MS and il.s treatment. Drs. McPherson and Seland and their team of specialisls arc trying to find out if a par- licular group of amino acids from (lie remaining ifc'I in (lie molecule prevent the. group of nine or the whole molecule from causing the disease in the guinea pigs, PREVENTS PISFASK "We have found that n por- tion of the molecule, if in- jected into the guinea pigs be- fore they are exposed lo the EAE factors, will prevent cer- tain aspects of the disease. However, so far, the inhibi- tory portion hasn't worked if it is injected after the guinea pig lias the disease." In Die clinical portion of the work, the doctors have studied tlic eftecLs of a prepa- ration known as anti-lhymo- cytc globulin, or ATG. when given Lo patients wiih MS, In Most prisoners repealers EDMONTON" (CP> Tvvo- Lhirrls of all prisoners in AllH-Tla in Uie year ended Mardl were1 I'ppcaler.s, .say.s a reporl of llic1 Ininian resources I't'scarcli council i Til 19119-70. says flic rrpnrl. pci cenl proliatioiiers con- llicir jn'rind.s Hiicces.stul- ly, siigpcslinp "Ihis form o( Irea'.men! may be among flio mosl successful of nil.'' 1 -Alllimipli Iraiv-ins ami Jlclis comprise less than five per cenl i j of Ihe population they account j for almost 50 per cent of im j priionmerts. Ujo report said. j Evidence indicates I'.iat our jailf are pcriretuating a kind of i criminal suh culture .cro- j aled in part by the 50 called criminal inclina lions of its I members and bolstered by the treatment these people receive! from the law enforcement and j i correctional system of locietv." .some cases, patients who have not responded lo the reg- ular course of treatment have had "some spectacular re- sults." In one insUmcc. a young fiirl wlio was conlincd lo .1 wheelchair because of loss of slrenfjlh in her legs and arms is again able to walk with only slight stiffness. "However, the course of MS Is so variable it often has natural and spontaneous re- missions." CONTROLS SET UP Patients who are receiving the treatment have to be matched with another similar group who rlo not receive Uie ATG. Both groups have to be examined thoroughly and carefully every two weeks to a month for at least a year after treatment is ATG is an experimental and untried drug and little Is known about Ihe side effects Dial may occur, Dr. JUc- Pherson said. Using the control experi- ments, the doctors have not found that ATG offers any short-term improvements over conventional methods of treatment for most patients. In the longer perioo. Ihe re- sults arc not yet complete enough to tell. However, for a Ihird group -ivith acute disease who are not responding to Uie regular trentmenl-ATG has shown some '-conservatively positive'' results. "U is another chance, an extra card up our sleeves." it yourself CEILING TILES 1 DOMTAR "STARDUST" ACOUSTIC Decorative, prefinished, white tiles absorb sound, cut down noise. tiles gj jM QC I in cartons of 64 iq. ft. I Sale, per carton [U 11 DOMTAR PREFINISHED Silver glinl jquare-lcx ceiling panels. 4'x4'. 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