Page 8 of 1 Sep 1997 Issue of Colorado Springs Beacon in Colorado-Springs, Colorado

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Colorado Springs Beacon (Newspaper) - September 1, 1997, Colorado Springs, Colorado 8 the Beacon september i 997 health the wonder drug turn Sion years old by eve c. Lash staff writer once upon a time in 1897, there was a Young Bayer company chemist named Felix Hoffmann. He discovered a stable form of Acety salicylic acid the Active ingredient in aspirin. Hoffmann had been seeking a pain relieving medication for his fathers debilitating rheumatism. Not Only did the drug ease his fathers pain and inflammation but when it was marketed As aspirin by Bayer two years later it quickly became the worlds most popular pain reliever. One Century after Hoffmanns discovery aspirin continues to be the subject of extensive medical research and has gained recognition for life saving properties As a cardiac care regimen for millions of people. This Little wonder drug remains at the forefront for Bayer As the major marketer of aspirin worldwide. Bayer continues to reinvent its application with research and education aimed at discovering new uses for its Little White drug. It helps to prevent everything from heart attacks to certain types of cancer a and even alzheimer a disease. From Willow tree to Nobel prize aspirin a ingredient Acety salicylic acid Casais the commercially synthesized form of a naturally occurring compound whose uses can be traced 2,000 years. The compound called Lalicin is found in the White Willow tree. Around 200 b.c., Hippocrates the greek physician known As the father of Medicine discovered that chewing on Willow bark could relieve pain and fever. Although Asa was a proven pain reliever no one really knew How it worked until More than 70 years after Hoffmanns discovery. In 1971, British pharmacologist John vane discovered that the anti inflammatory properties of Asa result from its ability to inhibit the body a production of certain chemical mediators Prosta Glandino that promote inflammation and therefore cause pain. Vane received the Nobel prize for Medicine in 1982 for this medical research breakthrough. Sayer and aspirin 11 billion Bayer trademarked a a aspirin in Germany on March 6, 1899. The name comes from a a a for a a acetyl and a a spire from a spirea a a Plant offering a natural source of Lalicin. The drug made its debut in 1899 As a powder and by 190 3, Bayer a Brand of aspirin became the first major drug to be marketed As a convenient Tablet. Future use while the pain and inflammation relieving uses of aspirin continue to expand the role of the drug in the prevention of major disease has become a research topic with increasing potential. The most conclusive evidence of aspirin a preventive benefits comes from research related to its ability to help prevent heart attacks and strokes. In the United states alone it is estimated that As Many As 10,000 additional lives could be saved annually by broader use of aspirin in appropriate people who Are at risk of heart attack and stroke. Many of the nations 1.5 million heart attacks each year could be prevented providing additional years of healthy productive living. Bayer aspirin is produced by the Bayer corporation consumer care division at facilities in Myerstown a. Bayer corporation head i quartered in Pittsburgh is a research based company with businesses in health care chemical and imaging technologies. The company had sales last year of $9.4 billion and employs 24,000 people. Bayer corporation is a member of the worldwide Bayer group a $31-an Early and billion chemical and pharmaceutical company for Bayer aspirin. Baselj in Leve Kusen Germany. Q Bayer chemist Felix Hoffmann. It All began with a Young chemists quest to ease his father s pain during its first decade aspirin was found to be so effective As a Medicine by physicians worldwide it became popularly used for Range of ailments from headaches fever inflammation pleurisy and tonsillitis to tuberculosis gonorrhoea and gout. Affordable for practically everyone aspirin quickly became a household necessity for Safe and effective pain Relief. Tens of thousands of people in fact took aspirin during several major influenza epidemics in the Early 20th Century. Today in the United states As Many As 29 billion tablets Are consumed each year. As the worlds primary aspirin producer Bayer has manufactured More than la billion tablets in the United states alone. Today despite a highly competitive analgesics Market aspirin sales have continued to grow while competitors such As acetaminophen and ibuprofen have had relatively Flat sales during the past three years according to research compiled by Bayer

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